Heart failure (HF) has become increasingly common. The traditional heart failure treatments need an update to prevent and manage the patient’s condition. Sacubitril and Sacubitril Valsartan Sodium are two revolutionary heart disease drugs that are more effective and approved by the FDA.
Over 64 million people globally suffer from heart failure (source). Therefore, there is an increasing demand for drugs that can do better than the traditional ACE inhibitors and beta-blockers. Sacubitril and Sacubitril Valsartan Sodium are now used for heart disease prevention in HF patients to help them overcome the symptoms and live a normal life.
What is Sacubitril?
Sacubitril is a neprilysin inhibitor. Thus, it prevents the neprilysin enzyme from breaking down the peptides responsible for vasodilation and fluid buildup. It is also known by its brand names Entresto and Neparvis. Sacubitril is combined with other medicines, like Valsartan, to create better heart disease drugs.
Thus, Sacubitril has been actively used in heart failure treatment. It reduces the risk of hospitalization, blood fluid buildup, and high blood pressure.
What is Sacubitril Valsartan Sodium?
Sacubitril Valsartan Sodium combines Sacubitril and Valsartan, a popular heart disease drug. It is commonly known by its brand name Entresto. Due to its effectiveness, Sacubitril Valsartan is widely used in heart failure treatments.
Valsartan is an angiotensin II receptor blocker (ARB). It prevents the hypertensive effect of the angiotensin II protein. Therefore, Valsartan reduces blood pressure and cardiac activities for heart disease prevention. It is one of the commonly used heart disease drugs used with other drugs like Sacubitril.
To make heart failure treatments more manageable and effective, both Sacubitril and Valsartan are combined in Sacubitril Valsartan Sodium.
The Sacubitril Valsartan Sodium is the FDA-approved drug under the angiotensin receptor neprilysin inhibitor (ARNI) category (source). It protects the peptides and inhibits angiotensin II for better heart activities. As per the test, they have been effective on patients with heart failure ejection fraction; both preserved (HFpEF) and reduced (HFrEF)
Benefits of Sacubitril and Sacubitril Valsartan Sodium
Sacubitril and Sacubitril Valsartan Sodium help with two crucial causes of heart failure: a lack of peptides and higher angiotensin II receptors. Therefore, patients susceptible to heart failure and diseases can benefit from these drugs. The following are a few of these benefits.
Strengthen heart functionality
These two drugs affect the blood pressure and vasodilation. Therefore, with proper dosage, your heart can function properly, without excessive contraction leading to healthy blood pressure and other heart activities. Continuous consumption under prescription can help with heart disease prevention.
Reduce heart failure
The improved heart performance significantly reduces the effect of advanced heart disease. The better heart activity and blood pressure reduce the threats associated with heart disease and act as a prevention against advanced heart failure.
Reduce the need for hospitalization
The cost associated with heart-related hospitalization is much higher. Therefore, advanced heart disease treatments, including Sacubitril and Sacubitril Valsartan Sodium, can help improve heart health and reduce the number of hospital visits. Furthermore, it also helps overcome the psychological toll on heart patients.
Improved quality of life
When the blood pressure and vasodilation are regulated, the patients are likely to feel better, less tired, have regular breathing, and overall be healthier to resume their regular activities. Thus, regular dosage can help heart patients live a better life with some lifestyle changes.
APIs play a vital role in the quality of any drug; the heart disease drugs are no different. If you want to create highly effective drugs for heart failure treatment, you must choose the best Sacubitril and Sacubitril Valsartan Sodium APIs.
Where to find Sacubitril and Sacubitril Valsartan Sodium APIs for heart failure treatments?
When choosing an API manufacturer, you need to choose the best because a minor inconsistency can affect the efficacy of the drug and its approval in your desired market. That’s why many pharma companies choose Chemox Pharma as their API and Intermediate partners. We create custom APIs based on your pharmacopoeia standard requirements in our WHO-GMP approved R&D and manufacturing facility. We supply high-quality heart treatment APIs, including Sacubitril and Sacubitril Valsartan Sodium, with custom packaging. Contact us to know more!
Conclusion
Heart diseases are becoming more common due to stress, poor eating habits, and lower immune strength. Therefore, heart failure treatments need to be advanced to help heart patients feel better and live a normal life. Sacubitril and Sacubitril Valsartan Sodium are two popular heart disease drugs. It’s because they are angiotensin receptor neprilysin inhibitors (ARNI); they are more effective than the traditional treatments. They help with blood pressure and vasodilation, and prevent fluid buildup in the heart. Customize your APIs based on your pharmacopoeia requirements with Chemox Pharma. Contact us now for a consultation call!
FAQ
What is the use of the Sacubitril Valsartan Sodium tablet?
The Sacubitril Valsartan Sodium tablet, popularly known as Entresto, is used for the treatment of heart disease. It’s an angiotensin receptor neprilysin inhibitor (ARNI) made by combining Sacubitril and Sacubitril Valsartan Sodium. It prevents the peptide breakdown and angiotensin II receptors for better heart function.
Is Sacubitril a blood thinner?
No, Sacubitril isn’t a blood thinner. It is a neprilysin inhibitor that stops the breakdown of the peptides responsible for healthy vasodilation and blood pressure. It is one of the common medicines used for heart failure treatment.
Can you create Sacubitril Valsartan Sodium API with custom pharmacopoeia standards?
Absolutely! Chemox Pharma is known for its WHO-GMP approved R&D and manufacturing facility in Dahej. We can help you create APIs and Intermediates with a custom pharmacopoeia standard and packaging. We can help you create Sacubitril Valsartan Sodium API as per the INH, BP, USP, IP, and EP standards. Contact us now for more details.
What does Sacubitril do for the heart?
Sacubitril is a neprilysin inhibitor that prevents the neprilysin enzyme from breaking down the peptides. These peptides help regulate the heart’s activities. It enables you to manage your blood pressure. It works better when used along with Valsartan.
