SACUBITRIL

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SACUBITRIL

SACUBITRIL
Chemical name: 4-(((2S,4R)-1-([1,1′-Biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl) amino)-4-oxobutanoic acid, (2R,4S)-4-[(3-Carboxy-1-oxopropyl) amino]-4-[(p-phenyl phenyl) methyl]-2-methyl butanoic acid ethyl ester
Cas number: 149709-62-6
Molecular formula: C24H29NO5
Molecular weight: 411.49
Therapeutic uses: Used to treat Heart Failure
Specifications: IP/BP/EP/USP
Appearance: White to beige powder
Storage: 2-8 °C
Therapeutic Class: Antihypertensive drug

Description:

Sacubitril [Cas No. 149709-62-6] is a antihypertensive API manufactured to treat advanced cardiovascular care. Sacubitril is a nepriysin inhibitor prodrug used in combination with Valsartan to treat chronic heart failure and hypertension. When Sacubitril is metabolized into its active form that is sacubitrilat, it inhibits the enzyme mainly responsible for degrading natriuretic peptides. This inhibition promotes vasodilation and natriuresis leading to reduction in blood pressure, enhanced cardiac output as well as low risk of heart failure.

Chemox Pharma delivers high-quality Sacubitril API that meets all global regulatory documents such as DCGI, WHO-GMP, FDA. Chemox Pharma supplies innovative and competitively priced solutions to meet the requirements of global pharmaceutical industries. The API products manufactured by Chemox Pharma is trusted worldwide and reflect our global footprints and reputation.