SACUBITRIL VALSARTAN SODIUM

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SACUBITRIL VALSARTAN SODIUM

SACUBITRIL VALSARTAN SODIUM
Chemical name: N-((2′-(1H-tetrazol-5-yl)-[1,1′-biphenyl]-4-yl) methyl)-N-pentanoyl-L-valinate compound with 4-(((2S,4R)-1-([1,1′-biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl) amino)-4-oxobutanoate (1:1) trisodium Hemi pentahydrate
Common Name: Entresto
Cas number: 936623-90-4
Molecular formula: C48H58N6O8
Molecular weight: 847.03
Therapeutic uses: Used to treat Heart Failure
Specifications: IP/BP/USP
Appearance: White to Off-White Solid Powder
Storage: Room temperature <25°C
Therapeutic Class: Dual-acting cardiovascular agent

Description:

Sacubitril Valsartan Sodium [Cas No. 936623-90-4] is a combination API that treats chronic heart failure as well as hypertension. This API possess dual acting therapeutic innovation and includes Valsartan, known as angiotensin II receptor blocker [ARB] with Sacubitril, a neprilysin inhibitor creates formulation which is clinically known as ARNI [ angiotensin receptor-neprilysin inhibitor]. This combination of Valsartan and Sacubitril promotes vasodilation, enhanced cardiac output and natriuresis. Sacubitril Valsartan Sodium has strong efficacy in reducing heart failure and improves ejection fraction.

Chemox Pharma is a trusted supplier and manufacturer of Sacubitril Valsartan Sodium and provides GMP- compliant pharma grade high-quality API. Chemox Pharma has well equipped R&D Centre mainly focusing on process development, quality improvement and cost optimization. Chemox Pharma provides competitive price solutions that meets the requirement of global pharmaceutical industries.