Tadalafil Citrate [Cas No. 171596-29-5] is a pharma grade phosphodiesterase type 5 [PDE5] inhibitor API which has potency in treating erectile dysfunction [ED] and pulmonary arterial hypertension [PAH]. Tadalafil Citrate has pyrazinopyridoindole and benzodioxol derivative that enhances nitric acid [NO] mediated vasodilation by inhibiting cGMP, resulting in smooth muscle relaxation and increase blood flow. Tadalafil Citrate is well known for its long duration action for up to 36 hours and possess dual benefits in urological health and cardiopulmonary support. Tadalafil Citrate is globally marketed by brand name Cialis [for ED] and Adcirca [for PAH] and usually targets vascular performance, sexual wellness and pulmonary function.
Chemox Pharma is the largest manufacturer of Tadalafil Citrate API in IP/BP/EP/USP grade and ensures high-purity products with highest level of compliance. Chemox Pharma offers global regulatory supports and reliable supply chain solutions – establishing us as a trusted partner by pharmaceutical companies over 90 countries, reflecting global footprints and reputation.
| Sr. No. | Description | Application |
|---|---|---|
| 1 | PDE5 inhibitor API | Erectile dysfunction formulations |
| 2 | Urology therapeutic drug substance | Pulmonary arterial hypertension therapy |
| 3 | Smooth muscle relaxant API | Male sexual health drugs |
| 4 | Vasodilator pharmaceutical ingredient | Vascular relaxation therapy |
| 5 | Urogenital therapeutic API | Urology combination formulations |
Tadalafil Citrate is widely used by pharmaceutical manufacturers in urology and cardiovascular formulations for erectile dysfunction and pulmonary hypertension management.
Tadalafil Citrate API should be handled according to standard pharmaceutical material safety and industrial hygiene procedures. Appropriate protective measures must be followed during handling and processing of the urology active pharmaceutical ingredient in GMP manufacturing environments.
Use appropriate personal protective equipment (PPE)
Avoid inhalation of powder and contact with skin or eyes
Handle in controlled pharmaceutical manufacturing areas
Follow GMP material handling procedures
Refer to Safety Data Sheet (SDS) for detailed safety guidance
This API is intended exclusively for pharmaceutical manufacturing and formulation use.
Tadalafil Citrate is a phosphodiesterase type-5 (PDE5) inhibitor that blocks the degradation of cyclic guanosine monophosphate (cGMP) in smooth muscle cells. Increased cGMP levels promote smooth muscle relaxation and vasodilation in the corpus cavernosum and pulmonary vasculature, improving blood flow. This mechanism supports its therapeutic use in erectile dysfunction and pulmonary arterial hypertension.
Handle in approved pharmaceutical manufacturing facilities
Avoid exposure without protective equipment
Prevent dust generation and inhalation
Follow GMP containment procedures
Dispose according to regulatory guidelines
Store in tightly closed containers
Protect from moisture and light
Maintain controlled room temperature
Keep in designated API storage areas
Follow GMP warehouse practices
Tadalafil Citrate API is used in pharmaceutical formulations for the treatment of erectile dysfunction and pulmonary arterial hypertension.
Yes, Chemox Pharma is a WHO-GMP certified Tadalafil Citrate API manufacturer and supplier in India serving global pharmaceutical companies.
The CAS number of Tadalafil is 171596-29-5, commonly supplied as the citrate salt for pharmaceutical formulations.
Tadalafil Citrate belongs to the phosphodiesterase-5 (PDE5) inhibitor class of urology therapeutic agents used in erectile dysfunction and pulmonary hypertension treatment.
It should be stored in tightly closed containers at controlled room temperature, protected from moisture and light, following pharmaceutical storage guidelines.
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