Dorzolamide Hydrochloride [Cas No. 130693-82-2] is a carbonic anhydrase inhibitor API widely used for treatment of glaucoma and ocular hypertension. Dorzolamide Hydrochloride inhibits carbonic anhydrase in the ciliary body by which it reduces aqueous humor production and lowers intraocular pressure [IOP]. When IOP is reduced, optic nerve is protected, and vision is preserved making Dorzolamide Hydrochloride a key component in both monotherapy and fixed dose combination treatment. Dorzolamide is administered topically and has good safety profile with targeted ocular action and systemic absorption is very low which makes it first choice for glaucoma therapy.
Chemox Pharma is a leading Dorzolamide Hydrochloride API Manufacturer in india. Also They provide global regulatory standards and quality specifications. Chemox Pharma also house a well-equipped R&D Centre, focused on process development, quality improvement, and cost optimization empowering us to meet the evolving needs of the global pharmaceutical industry.
| Sr. No. | Description | Application |
|---|---|---|
| 1 | Carbonic anhydrase inhibitor API | Glaucoma eye drop formulations |
| 2 | Ophthalmic therapeutic drug substance | Intraocular pressure reduction |
| 3 | Ocular hypotensive pharmaceutical ingredient | Ocular hypertension treatment |
| 4 | Antiglaucoma API | Combination ophthalmic drugs |
| 5 | Topical ocular enzyme inhibitor | Eye pressure control therapy |
Dorzolamide is widely used by pharmaceutical manufacturers in ophthalmic formulations for glaucoma and ocular hypertension management.
Dorzolamide API should be handled according to standard pharmaceutical material safety and industrial hygiene procedures. Appropriate protective measures must be followed during handling and processing of the ophthalmic active pharmaceutical ingredient in GMP manufacturing environments.
Use appropriate personal protective equipment (PPE)
Avoid inhalation of powder and contact with skin or eyes
Handle in controlled pharmaceutical manufacturing areas
Follow GMP material handling procedures
Refer to Safety Data Sheet (SDS) for detailed safety guidance
This API is intended exclusively for pharmaceutical manufacturing and formulation use.
Dorzolamide is a carbonic anhydrase II inhibitor that reduces aqueous humor production in the ciliary processes of the eye. By inhibiting carbonic anhydrase, it decreases bicarbonate ion formation and fluid transport, leading to reduced intraocular pressure. This mechanism supports its therapeutic use in glaucoma and ocular hypertension treatment.
Handle in approved pharmaceutical manufacturing facilities
Avoid exposure without protective equipment
Prevent dust generation and inhalation
Follow GMP containment procedures
Dispose according to regulatory guidelines
Store in tightly closed containers
Protect from moisture and light
Maintain controlled room temperature
Keep in designated API storage areas
Follow GMP warehouse practices
Dorzolamide API is used in ophthalmic pharmaceutical formulations for the treatment of glaucoma and ocular hypertension by reducing intraocular pressure.
Yes, Chemox Pharma is a WHO-GMP certified Dorzolamide API manufacturer and supplier in India serving global pharmaceutical companies.
The CAS number of Dorzolamide API is 120279-96-1.
Dorzolamide belongs to the carbonic anhydrase inhibitor class of ophthalmic therapeutic agents used in glaucoma management.
It should be stored in tightly closed containers at controlled room temperature, protected from moisture and light, following pharmaceutical storage guidelines.
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