5-(4′-(Bromomethyl)-[1,1′-biphenyl]-2-yl)-1-trityl-1H-tetrazole (TTBB) (CAS 124750-51-2)

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5-(4′-(Bromomethyl)-[1,1′-biphenyl]-2-yl)-1-trityl-1H-tetrazole (TTBB) (CAS 124750-51-2)

Sartan Family CAS 124750-51-2
API name/end use: Sartan family
Cas number: 124750-51-2
Molecular formula: C33H25BrN4
Molecular Weight: 557.48
Appearance: Solid Powder
Storage: Room Temperature (Recommended in a cool and dark place, <15°C)

Description:

Chemox Pharma is a trusted manufacturer and supplier of 5-(4′-(Bromomethyl)-[1,1′-biphenyl]-2-yl)-1-trityl-1H-tetrazole (TTBB) (Cas No.; 124750-51-2 ) intermediate which plays a key role in chemical synthesis of Losartan and Valsartan. Chemox Pharma provides high-quality intermediates that meet all global safety standards like WHO-GMP, FDA, DCGI.

Contact Chemox Pharma for pharma grade 5-(4′-(Bromomethyl)-[1,1′-biphenyl]-2-yl)-1-trityl-1H-tetrazole intermediate which complies with precision, consistency, purity and quality. We aim to create high quality products and innovative APIs and intermediate through continuous R&D following the latest WHO – GMP standards. We believe in delivering quality products with competitive prices and delivery on time.

Applications

Sr. No. Description Application
1 Tetrazole-biphenyl intermediate ARB API synthesis
2 Protected tetrazole building block Sartan drug manufacturing
3 Halogenated aromatic intermediate Medicinal chemistry synthesis
4 Pharmaceutical heterocyclic intermediate Cardiovascular drug development
5 Specialty chemical intermediate Fine chemical production

TTBB is widely used in pharmaceutical manufacturing as a key intermediate in the synthesis of angiotensin receptor blocker (ARB) active pharmaceutical ingredients.

Product Specifications

TTBB should be handled according to standard pharmaceutical intermediate and chemical safety procedures. Appropriate industrial hygiene and protective measures must be followed during handling, processing, and synthesis operations.

  • Use suitable personal protective equipment (PPE) during handling

  • Avoid inhalation of dust or vapors and contact with skin or eyes

  • Handle in controlled, well-ventilated environments

  • Follow chemical material handling protocols

  • Refer to Safety Data Sheet (SDS) for detailed safety guidance

This compound is intended strictly for pharmaceutical intermediate and industrial chemical use.

Mechanism of Actions

As a tetrazole pharmaceutical intermediate, TTBB does not possess direct pharmacological activity. It functions as a protected tetrazole-biphenyl building block in multi-step organic synthesis pathways for ARB class active pharmaceutical ingredients. The bromomethyl group enables selective substitution and coupling reactions, while the trityl-protected tetrazole ensures controlled functionalization during drug synthesis processes.

Safety Precautions

  • Handle in approved chemical or pharmaceutical manufacturing facilities

  • Avoid exposure without protective equipment

  • Prevent dust formation and inhalation

  • Follow industrial chemical safety procedures

  • Dispose according to regulatory guidelines

Storage

  • Store in tightly closed containers

  • Protect from moisture and light

  • Maintain cool, dry storage conditions

  • Keep in designated chemical storage areas

  • Follow standard warehouse practices

FAQs

What is TTBB (CAS 124750-51-2) used for?

TTBB is a tetrazole pharmaceutical intermediate used in the synthesis of angiotensin II receptor blocker (ARB) active pharmaceutical ingredients and other cardiovascular drug compounds.

Is Chemox Pharma a manufacturer of TTBB intermediate?

Yes, Chemox Pharma manufactures and supplies 5-(4′-(Bromomethyl)-[1,1′-biphenyl]-2-yl)-1-trityl-1H-tetrazole (TTBB) (CAS 124750-51-2) with high purity for pharmaceutical and chemical manufacturing applications.

What type of compound is TTBB?

TTBB is a tetrazole-biphenyl heterocyclic intermediate used as a protected tetrazole building block in sartan class API synthesis.

What is the CAS number of TTBB?

The CAS number of 5-(4′-(Bromomethyl)-[1,1′-biphenyl]-2-yl)-1-trityl-1H-tetrazole is 124750-51-2.

How should TTBB pharmaceutical intermediate be stored?

It should be stored in tightly sealed containers in a cool, dry place protected from moisture and light, following standard chemical storage practices.

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