Benfotiamine [CAS No: 22457-89-2], also known as S-benzoylthiamine O-monophosphate, is a highly bioavailable lipid-soluble derivative of Vitamin B1 (Thiamine). As an advanced thiamine analogue, Benfotiamine plays an essential role in maintaining healthy nerve cell metabolism and supporting normal cellular energy production. It is widely used to enhance nerve function, cognitive performance, and metabolic balance, particularly in conditions associated with oxidative stress and high blood glucose levels.
Research has shown that Benfotiamine significantly reduces the formation of advanced glycation end products (AGEs) and restores transketolase activity, which protects neurons from glucose-induced cellular damage. This mechanism is crucial in managing neuropathic discomfort, improving nerve conduction, and supporting long-term vascular, brain, and metabolic health. In addition, Benfotiamine has demonstrated benefits in promoting mood stability, mental clarity, and overall neuroprotection.
Chemox Pharma is a leading manufacturer of Benfotiamine and adheres to international regulatory standards including WHO-GMP, FDA, and DCGI. Our technologically advanced production facility and in-house R&D Centre are dedicated to continuous process improvement, quality enhancement, and cost optimization—enabling us to meet the evolving needs of global pharmaceutical and nutraceutical partners with high-purity, consistently reliable material.
| Sr. No. | Description | Application |
|---|---|---|
| 1 | Vitamin B1 derivative ingredient | Nutritional supplements |
| 2 | Neuroprotective nutraceutical API | Diabetic neuropathy support |
| 3 | Antioxidant vitamin ingredient | Oxidative stress management |
| 4 | Thiamine bioavailability enhancer | Vitamin B1 deficiency formulations |
| 5 | Neurological health ingredient | Nerve health supplements |
Benfotiamine is widely used by pharmaceutical and nutraceutical manufacturers in formulations for nerve health, metabolic support, and antioxidant therapy.
Benfotiamine should be handled according to standard pharmaceutical material safety practices and industrial hygiene procedures. Proper protective measures must be followed during handling, processing, and manufacturing operations involving this vitamin derivative ingredient.
Use appropriate personal protective equipment (PPE) during handling
Avoid inhalation of powder and direct contact with skin or eyes
Handle in controlled, well-ventilated environments
Follow GMP material handling procedures
Refer to Safety Data Sheet (SDS) for detailed safety information
This material is intended for pharmaceutical and nutraceutical manufacturing use only.
Benfotiamine is a lipid-soluble derivative of thiamine (vitamin B1) that exhibits higher bioavailability than water-soluble thiamine salts. After absorption, it is converted into active thiamine diphosphate, a coenzyme involved in carbohydrate metabolism and cellular energy production. Benfotiamine reduces advanced glycation end products (AGEs) formation and oxidative stress, thereby supporting nerve function and metabolic health.
Handle in approved pharmaceutical manufacturing facilities
Avoid exposure without protective equipment
Prevent dust generation and inhalation
Follow GMP containment and handling procedures
Dispose according to regulatory requirements
Store in tightly closed containers
Protect from moisture and light
Maintain cool, dry storage conditions
Keep in designated pharmaceutical storage areas
Follow GMP warehouse practices
Benfotiamine is a fat-soluble derivative of vitamin B1 used in nutraceutical and pharmaceutical formulations for managing diabetic neuropathy, oxidative stress, and vitamin B1 deficiency.
Yes, Chemox Pharma supplies high-quality pharmaceutical and nutraceutical grade Benfotiamine manufactured under GMP-compliant processes for global supplement and pharmaceutical companies.
The CAS number of Benfotiamine is 22457-89-2.
Benfotiamine belongs to the vitamin B1 (thiamine) derivative class and is widely used in nutritional supplements and neuropathy management formulations.
Benfotiamine should be stored in tightly sealed containers in a cool, dry place, protected from moisture, heat, and direct light, following standard pharmaceutical storage conditions.
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