Atorvastatin Calcium Salt is active pharmaceutical crystalline powder which is widely acclaimed for its lipid-lowering efficacy. It is a competitive inhibitor of HMG-CoA reductase-which is the key enzyme involved in the mevalonate pathway of cholesterol synthesis. Atorvastatin Calcium Salt is a heptanoic acid derivative with pyrrole moiety which plays a pivotal role as an anti-cholesteric agent. It significantly reduces serum LDL -cholesterol, while moderately increases HDL levels. It is the primary ingredient used in the prevention and management of atherosclerotic cardiovascular diseases for high-risk individuals.
Chemox Pharma is the leading manufacturer of Atorvastatin API in IP/BP/EP/USP standards. We offer high-quality products with high levels of compliance. Our API products are trusted by pharmaceutical industries, which reflects our global footprints and reputation. Our facilities follow the standard regulations of the world like DCGI, WHO-GMP, FDA.
Atorvastatin Calcium API Applications in Pharmaceuticals
| Sr. No. | Description | Application |
|---|---|---|
| 1 | Lipid-lowering statin API | Hypercholesterolemia treatment |
| 2 | Cardiovascular therapeutic API | Prevention of cardiovascular disease |
| 3 | Antihyperlipidemic drug substance | Reduction of LDL cholesterol |
| 4 | Dyslipidemia treatment API | Management of mixed dyslipidemia |
| 5 | Atherosclerosis therapy API | Prevention of plaque formation |
Atorvastatin Calcium is widely used by pharmaceutical formulation companies in the production of statin-based cardiovascular medications.
Atorvastatin Calcium API should be handled in accordance with pharmaceutical material safety guidelines and standard industrial hygiene practices applicable to active pharmaceutical ingredients.
Key Safety Information
Use appropriate personal protective equipment (PPE) during handling
Avoid inhalation of API dust or direct skin/eye contact
Handle in controlled manufacturing environments
Follow GMP material handling procedures
Refer to Safety Data Sheet (SDS) for detailed guidance
This pharmaceutical API is intended exclusively for industrial pharmaceutical manufacturing and formulation use.
Atorvastatin Calcium is a statin class antihyperlipidemic agent that inhibits HMG-CoA reductase, the key enzyme responsible for cholesterol biosynthesis in the liver. By blocking cholesterol synthesis, it increases hepatic LDL receptor expression and enhances clearance of circulating low-density lipoprotein (LDL) cholesterol.
This mechanism contributes to reduced plasma cholesterol levels and decreased risk of cardiovascular events.
Handle only in approved pharmaceutical facilities
Avoid exposure without PPE
Prevent environmental contamination
Follow GMP containment procedures
Dispose according to regulatory requirements
Atorvastatin Calcium API is used in pharmaceutical formulations for lowering cholesterol and preventing cardiovascular diseases.
Yes, Chemox Pharma is a WHO-GMP certified Atorvastatin Calcium API manufacturer and supplier in India serving global pharmaceutical companies.
The CAS number of Atorvastatin Calcium API is 134523-00-5.
Atorvastatin belongs to the statin class of antihyperlipidemic agents used for cholesterol reduction.
It should be stored in tightly closed containers at controlled room temperature, protected from moisture and light.
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