Our vision is the most important asset. However, one can experience permanent vision loss when they have Glaucoma. Its slow progression often goes unnoticed by the patients and results in significant vision loss. However, modern medicine has found topical beta blockers and Dorzolamide effective for Glaucoma treatment.
In this blog, we will discuss Glaucoma and how to reduce eye pressure with the best topical beta blockers and Dorzolamide. If you are a pharma company wanting to create Dorzolamide, Chemox Pharma provides Dorzolamide API with your desired pharmacopoeia standards. Contact us now to know more.
What is Glaucoma?
Glaucoma is a chronic medical condition of the eyes that might lead to permanent vision loss. It is caused when the intraocular pressure (IOP), due to fluid buildup, is higher, affecting the function of the optic nerves. When detected early, vision can be saved by managing the pressure and fluid drainage.
There are two types of Glaucoma: Primary (no other medical condition) and Secondary (caused by other medical conditions). Let’s understand them better.
Types of Primary Glaucoma
- Open-angle Glaucoma has no particular cause or symptoms. Patients often don’t show symptoms till severe vision loss happens. Mostly caused when the fluid buildup doesn’t drain fast enough.
- Normal-tension Glaucoma occurs in people with normal eye pressure.
- Angle-closure, or narrow-angle or acute Glaucoma, is when there is pain, redness, and sudden blurry vision. You need immediate attention.
- Congenital Glaucoma happens in babies and can be treated with surgery.
Types of Secondary Glaucoma
- Neovascular Glaucoma happens when the eyes have extra blood vessels that put pressure on the optic nerves.
- Pigmentary Glaucoma happens when the iris flakes off and blocks the fluid drainage system of the eyes.
- Exfoliation glaucoma, or pseudoexfoliation, happens in patients with exfoliation syndrome. Here, some material blocks the eye drainage system, causing an increase in pressure.
- Uveitic Glaucoma happens in patients with uveitis, where scar tissue can block the eye fluid drainage system.
What is the use of beta blockers for Glaucoma?
The beta blockers are used as a secondary measure to control Glaucoma. These blockers inhibit beta-adrenergic receptors, forming aqueous humor fluid in the eyes. Therefore, they are widely used in creating glaucoma eye drops to control and reduce pressure on the optic nerve.
Which are the best topical beta blockers for Glaucoma Treatment?
The following are a few topical beta blockers used for treating Glaucoma:
Timolol
Timolol is one of the standard beta blockers used to reduce the production of aqueous humor in the eyes. Therefore, it reduces the pressure in the eyes. It is often used with other treatments like Dorzolamide to create effective glaucoma eye drops.
Betaxolol
Betaxolol is another popular Glaucoma treatment as it blocks the selective beta-1 adrenergic receptor, reducing the aqueous humor in the eye. It is a widely used glaucoma eye drop to reduce the pressure on the optic nerves.
Levobunolol
Levobunolol is another beta-blocker that reduces the eye’s intraocular pressure (IOP) by reducing the aqueous humor fluid. It provides relief from the pain and preserves the vision.
What’s the role of Dorzolamide API in Glaucoma Treatment?
Dorzolamide API is used to create Dorzolamide for the treatment of Glaucoma. The efficiency of the topical beta blockers can be improved when combined with Dorzolamide.
How does Dorzolamide work?
Dorzolamide is a carbonic anhydrase inhibitor (CAI) that reduces the production of aqueous humor in the eye. Therefore, it reduces the pressure in the eyes and prevents permanent vision loss. They are available under the brand names Cosopt and Trusopt.
Dorzolamide is one of the best medicines for creating a combination treatment for glaucoma.
The rising cases of Glaucoma have led to a rise in demand for drugs like Dorzolamide. As per the source, the current market demand for this drug is USD 1.2 billion in 2024 and is expected to reach USD 2.5 billion by 2033. If you want to enter this market, you’ll need high-quality Dorzolamide API. That’s where Chemox Pharma can help you!
Get your customized Dorzolamide API at Chemox Pharma
Chemox Pharma is a WHO-GMP approved Intermediate and API manufacturer in India. We have been trusted by customers from 20+ countries for our quality assurance and timely delivery. We can help you customize the pharmacopoeia standards of our pharma products based on your needs. You can also customize the packaging based on your needs. Our delivery partners ensure that your order reaches you safely without any contamination.
We can create Dorzolamide APIs in IP, BP, and USP pharmacopoeia standards to help you expand into global markets. Contact us now to know more!
Conclusion
Intraocular pressure (IOP) or eye pressure caused by the aqueous humor fluid in the eyes can lead to pain and permanent vision loss. That’s where the beta blockers like Timolol, Betaxolol, and Levobunolol with carbonic anhydrase inhibitor (CAI) like Dorzolamide can help you reduce the fluid and preserve vision. Both of these blockers reduce the fluid in the eyes and reduce the pressure. Chemox Pharma can help you create Dorzolamide API with custom pharmacopoeia standards. Contact us now to know more.
FAQ
What are topical beta blockers for the eyes?
The topical beta blockers for the eyes are used for Glaucoma treatment. They inhibit the production of aqueous humour in the eyes because excessive fluid creates pressure that might cause permanent vision loss.
How to reduce eye pressure?
The doctors can prescribe beta blockers or Dorzolamide eyedrops to reduce the liquid. However, in many cases, they can also suggest laser treatment for better results. Managing any underlying disease is also necessary to control this eye pressure. Get your eyes checked regularly to identify any issues in the early stages.
Can Dorzolamide and beta blockers be used together?
Absolutely! Dorzolamide and beta blockers like Timolol are combined to reduce the aqueous humor fluid in the eyes to treat Glaucoma.
Where can I find Dorzolamide API?
Chemox Pharma is the best place to find high-quality Dorzolamide API to create efficient Dorzolamide medicine. We can customize the quality and packaging based on your desired pharmacopoeia standards. Contact us now to know more.
