Hear failures have become one of the most common news headlines. Young people are also facing heart problems. Lifestyle choices and chronic stress are taking a toll on them. Therefore, there is a need for effective cardiovascular drugs. But what makes an effective heart failure treatment? Through effective APIs!
In this blog, we will discuss the top 5 APIs used to create cardiovascular drugs. Chemox Pharma is a trusted Atorvastatin API manufacturer known for its range of commercial anti-cholesterol APIs and some heart failure treatment APIs. Let’s start by understanding the demand for heart treatment APIs like Atorvastatin, Fenofibrate and more.
The market demand for cardiovascular drugs
As per the reports, cardiovascular diseases have caused 28.1% of deaths in India. There has been a significant increase in the number of patients with heart diseases and sudden death due to heart attacks. Therefore, there is an increasing demand for effective drugs, and thus demand for effective APIs to create those drugs. India has been exporting cardiovascular medicines to different countries.
Chemox Pharma is a trusted Atorvastatin API manufacturer, known for its WHO-GMP approved state-of-the-art labs and manufacturing units. We have five commercially available cardiovascular APIs to make effective and accessible CVD medicines.
Top 5 Cardiovascular APIs by Chemox Pharma
1. Atorvastatin
Atorvastatin API is used to create anti-cholesterol medicines. It is commonly known as Atorvastatin and is available under brand names like Atorvaliq, Caduet, Lipitor, and Lypqozet.
Atorvastatin is a statin medication widely used to reduce the production of cholesterol. It is an HMG-CoA Reductase inhibitor that helps lower your body’s cholesterol and lipid levels. It is one of the first treatments used for CVDs and high cholesterol. It is often used with other treatments like Fenofibrate.
Chemox Pharma is a trusted atorvastatin manufacturer in India. We have filed DMFs to ensure that our Atorvastatin API meets the regulatory standards. We have exported our APIs to 20+ countries, as we can customize the API based on your regulatory standard requirements.
2. Fenofibrate
Fenofibrate is an anti-cholesterol API commercially developed and exported by Chemox Pharma. It is available under Antara, Cholib, Fenoglide, Lipidil Supra, Lipofen, Pravafenix, Tricor, and Triglide brand names.
The Fenofibrate API activates the PPARα receptors, responsible for breaking down the lipids (fat). Therefore, it is widely used for the treatment of hypertriglyceridemia and mixed dyslipidemia. In both conditions, the blood has atherogenic lipids that increase the risk of heart disease.
While Chemox Pharma follows the WHO-GMP standards, we can customize the quality of APIs and Intermediates as per the US FDA, EMA, and other regulatory standards.
3. Sacubitril
Sacubitril API is used for heart failure treatment. It is available in the brand names Entresto and Neparvis. Sacubitril is combined with valsartan for better treatment.
Sacubitril API is a neprilysin inhibitor that prevents the breakdown of the peptides, hence reducing heart related complications. It is used to treat chronic heart failure and reduce the ejection fraction. Chemox Pharma develops Sacubitril API in our WHO-GMP approved labs to make it available to the pharma companies.
4. Sacubitril Valsartan Sodium
Sacubitril Valsartan Sodium is one of the emerging options for heart failure treatments. The sacubitril valsartan combination is known as angiotensin receptor-neprilysin lysine inhibitors (ARNIs). It is widely used in patients with hypertension and chronic heart failure (CHF). Chemox Pharma offers Sacubitril Valsartan Sodium to meet the global regulatory standards. Stay in touch with us for regular updates on the development of new cardiovascular APIs.
5. Mirabegron
Mirabegron is a β3-adrenergic receptor agonist popularly used to control an overactive bladder. However, it is found that stimulating the β3-adrenergic receptor in the heart can help with heart diseases like hypertension and even heart failure. It can also indirectly impact cardiovascular risk factors, like obesity and insulin resistance. More research is being conducted on the use of Mirabegron API for heart treatment drugs.
Conclusion
The number of patients suffering from cardiovascular diseases is increasing day by day. Therefore, there has been a demand for an effective cardiovascular drug for treatment. We have discussed the top 5 APIs, such as Atorvastatin, Fenofibrate, Sacubitril, Sacubitril Valsartan Sodium, and Mirabegron. All these APIs improve heart health and reduce the risk of heart failure. Chemox Pharma is a trusted Fenofibrate and Atorvastatin API manufacturer in India with a WHO-GMP approved manufacturing unit. We also offer Sacubitril, Sacubitril Valsartan Sodium, and Mirabegron. We can customize the quality to meet your desired regulatory standards. Contact us now for more information.
FAQ
Can Fenofibrate and Atorvastatin be given together?
Yes. Fenofibrate and Atorvastatin have been used together for heart treatments. They both help reduce the production of lipids (fats). Thus, they are used as anti-cholesterol medicines for heart patients. You should consult an expert regarding the dosage.
What are Atorvastatin and Fenofibrate used for?
Atorvastatin is an HMG-CoA Reductase inhibitor, and Fenofibrate activates PPARα receptors responsible for reducing cholesterol and lipid formation. Both of these APIs are used for heart treatments. They are both anti-cholesterol medicines and can be consumed together under a doctor’s guidance.
Who is the best Atorvastatin API manufacturer in India?
Chemox Pharma is a trusted Atorvastatin API manufacturer in India with WHO-GMP approval. We can customize the quality of the Atorvastatin API to meet the desired pharmacopoeia standards. We have been actively filing DMFs to expand our products and the countries we trade with. Contact us with your order details and get the best prices with custom packaging.
Which APIs are used for cardiovascular drugs?
Atorvastatin, Fenofibrate, Sacubitril, Sacubitril Valsartan Sodium, and Mirabegron are a few popular APIs used to create drugs for heart treatment. They reduce cholesterol and break down peptides, improving heart health.
