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Pantoprazole

CPPL / Product / Pantoprazole

Pantoprazole

Pantoprazole

Chemical Name: Pantoprazole

Other Names: Pantoprazole Sodium Sesquihydrate / 5-(Difluoromethoxy)-2-[(3,4-dimethoxypyridin-2-yl)methylsulfinyl]-1H-benzimidazole sodium salt sesquihydrate

CAS Number: 102625-70-7

Molecular Formula: C16H14F2N3NaO4S · 1.5H2O

Molecular Weight: 432.38

Therapeutic Uses: Gastroesophageal Reflux Disease (GERD), Peptic Ulcer, Zollinger-Ellison Syndrome

Specifications: IP / BP / USP

Appearance: White to off-white crystalline powder

Storage: Store below 25°C in a tightly sealed container. Protect from light and moisture.

Therapeutic Class: Proton Pump Inhibitor (PPI) | Anti-Ulcer Agent | Gastric Acid Secretion Suppressant

Description:

Pantoprazole [CAS No: 102625-70-7] is used to treat gastroesophageal reflux disease (GERD), erosive esophagitis, peptic ulcers and conditions involving excessive stomach acid such as Zollinger-Ellison syndrome. Pantoprazole is a proton pump inhibitor (PPI) which helps to reduce the amount of acid produced in the stomach. Pantoprazole selectively inhibits the H+/K+ ATPase enzyme system of gastric parietal cells, which is last step in acid production, resulting in sustained acid suppression and promotes healing of acid- related damage in the gastrointestinal tract.

Pantoprazole is well-tolerated and widely used in both short term and long term therapy and also is available in delayed release and injectable forms.

Chemox Pharma is a manufacturer of Pantoprazole, offering WHO-GMP certified facilities and a robust R&D infrastructure. Chemox Pharma is a reputed manufacturer of high – quality Active Pharmaceutical Ingredients (APIs) and advanced Intermediates with its multipurpose ultramodern state-of-the-art facility at Dahej Industrial area of Gujarat, India. Chemox Pharma pride on delivering innovative, reliable, and competitively priced solutions, ensuring timely delivery to meet the needs of the global pharmaceutical industry.

Applications

Sr. No. Description Application
1 Proton pump inhibitor API Gastroesophageal reflux disease (GERD) treatment
2 Anti-ulcer pharmaceutical ingredient Peptic ulcer therapy
3 Gastric acid suppression API Zollinger-Ellison syndrome management
4 Gastro-protective drug substance NSAID-induced ulcer prevention
5 Acid-reducing therapeutic API Gastrointestinal disorder formulations

Pantoprazole Sodium is widely used by pharmaceutical manufacturers in formulations for acid-related gastrointestinal disorders and ulcer management.

Product Specifications

Pantoprazole Sodium API should be handled according to standard pharmaceutical material safety and industrial hygiene procedures. Appropriate protective measures must be followed during handling and processing of the active pharmaceutical ingredient in GMP manufacturing environments.

  • Use appropriate personal protective equipment (PPE)

  • Avoid inhalation of powder and contact with skin or eyes

  • Handle in controlled pharmaceutical manufacturing areas

  • Follow GMP material handling procedures

  • Refer to Safety Data Sheet (SDS) for detailed safety guidance

This API is intended exclusively for pharmaceutical manufacturing and formulation use.

Mechanism of Actions

Pantoprazole Sodium is a proton pump inhibitor that selectively inhibits the H⁺/K⁺-ATPase enzyme system in gastric parietal cells. By blocking the final step of gastric acid secretion, it reduces stomach acid production and promotes healing of acid-related gastrointestinal mucosal damage. This mechanism supports its therapeutic use in GERD, peptic ulcer disease, and hypersecretory conditions.

Safety Precautions

  • Handle in approved pharmaceutical manufacturing facilities

  • Avoid exposure without protective equipment

  • Prevent dust generation and inhalation

  • Follow GMP containment procedures

  • Dispose according to regulatory guidelines

Storage

  • Store in tightly closed containers

  • Protect from moisture and light

  • Maintain controlled room temperature

  • Keep in designated API storage areas

  • Follow GMP warehouse practices

FAQs

What is Pantoprazole Sodium API used for?

Pantoprazole Sodium API is used in pharmaceutical formulations for reducing gastric acid secretion and treating acid-related disorders such as GERD and peptic ulcers.

Is Chemox Pharma a Pantoprazole Sodium API manufacturer in India?

Yes, Chemox Pharma is a WHO-GMP certified Pantoprazole Sodium API manufacturer and supplier in India serving global pharmaceutical companies.

What is the CAS number of Pantoprazole Sodium?

The CAS number of Pantoprazole Sodium API is 138786-67-1.

What is the therapeutic class of Pantoprazole API?

Pantoprazole belongs to the proton pump inhibitor (PPI) class of gastrointestinal therapeutic agents used to suppress gastric acid secretion.

How should Pantoprazole Sodium API be stored?

It should be stored in tightly closed containers at controlled room temperature, protected from moisture and light, following pharmaceutical storage guidelines.

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