MIRABEGRON

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MIRABEGRON

MIRABEGRON API
Chemical name: (R)-2-(2-Aminothiazol-4-yl)-N-[4-[2-[(2-hydroxy-2-phenylethyl) amino] ethyl] phenyl] acetamide, 2-Amino-N-[4-[2-[[(2R)-2-hydroxy-2-phenylethyl] amino] ethyl] phenyl]-4-thiazoleacetamide
Cas number: 223673-61-8
Molecular formula: C21H24N4O2S
Molecular weight: 396.51
Therapeutic uses: Beta-3 adrenergic agonist
Specifications: IP/EP/IH
Appearance: White to Off-White Solid
Storage: Room temperature <25°C
Class: β3-AR (β3 adrenergic receptor)

Description:

Mirabegron [Cas No. 223673-61-8] is a β3-adrenergic receptor agonist API widely used in treatment of urology. Mirabegron activates β3-adrenergic receptor in urinary bladder and helps in relaxation of detrusor muscle, resulting in increasing bladder storage capacity and reduces urinary urgency and frequency. Mirabegron treats overactive bladder [OAB] and is widely utilised in metabolic research and is key component that targets obesity, weight management as well as metabolic syndrome.

Chemox Pharma manufacturers high purity Mirabegron API in IP/BP/EP/USP standards. We offer high-quality products with high levels of compliance. Our API products are trusted by pharmaceutical industries, which reflects our global footprints and reputation. Our facilities follow the standard regulations of the world like DCGI, WHO-GMP, FDA.

Applications

Sr. No. Description Application
1 β3-adrenergic agonist API Overactive bladder treatment formulations
2 Urology therapeutic drug substance Urinary incontinence therapy
3 Bladder relaxant pharmaceutical ingredient Urgency and frequency control drugs
4 Urological smooth muscle relaxant API OAB symptom management
5 Selective β3 receptor agonist Urinary tract disorder formulations

Mirabegron is widely used by pharmaceutical manufacturers in formulations for overactive bladder and urinary dysfunction management.

Product Specifications

Mirabegron API should be handled according to standard pharmaceutical material safety and industrial hygiene procedures. Appropriate protective measures must be followed during handling and processing of the urology active pharmaceutical ingredient in GMP manufacturing environments.

  • Use appropriate personal protective equipment (PPE)

  • Avoid inhalation of powder and contact with skin or eyes

  • Handle in controlled pharmaceutical manufacturing areas

  • Follow GMP material handling procedures

  • Refer to Safety Data Sheet (SDS) for detailed safety guidance

This API is intended exclusively for pharmaceutical manufacturing and formulation use.

Mechanism of Actions

Mirabegron is a selective β3-adrenergic receptor agonist that stimulates β3 receptors in the detrusor smooth muscle of the urinary bladder. Activation of these receptors promotes relaxation of bladder muscle during the storage phase, increasing bladder capacity and reducing urinary urgency and frequency. This mechanism supports its therapeutic use in overactive bladder and urinary incontinence management.

Safety Precautions

  • Handle in approved pharmaceutical manufacturing facilities

  • Avoid exposure without protective equipment

  • Prevent dust generation and inhalation

  • Follow GMP containment procedures

  • Dispose according to regulatory guidelines

Storage

  • Store in tightly closed containers

  • Protect from moisture and light

  • Maintain controlled room temperature

  • Keep in designated API storage areas

  • Follow GMP warehouse practices

FAQs

<h3>What is Mirabegron API used for?</h3>
<p>Mirabegron API is used in pharmaceutical formulations for the treatment of overactive bladder and urinary incontinence by relaxing bladder smooth muscle.</p>

<h3>Is Chemox Pharma a Mirabegron API manufacturer in India?</h3>
<p>Yes, Chemox Pharma is a WHO-GMP certified Mirabegron API manufacturer and supplier in India serving global pharmaceutical companies.</p>

<h3>What is the CAS number of Mirabegron?</h3>
<p>The CAS number of Mirabegron API is 223673-61-8.</p>

<h3>What is the therapeutic class of Mirabegron API?</h3>
<p>Mirabegron belongs to the β3-adrenergic receptor agonist class of urology therapeutic agents used in overactive bladder management.</p>

<h3>How should Mirabegron API be stored?</h3>
<p>It should be stored in tightly closed containers at controlled room temperature, protected from moisture and light, following pharmaceutical storage guidelines.</p>

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