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Deflazacort

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Deflazacort

Deflazacort API Supplier

Chemical Name: Deflazacort

Other Names: 11β,21-Dihydroxy-2′-methyl-5′β-H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione

CAS Number: 14484-47-0

Molecular Formula: C25H31NO6

Molecular Weight: 441.52

Therapeutic Uses: Anti-inflammatory, Immunosuppressant

Specifications: IH

Appearance: White to off-white crystalline powder

Storage: Store below 25°C in a dry, tightly sealed container. Protect from light and moisture.

Therapeutic Class: Glucocorticoid | Anti-inflammatory Agent | Immunomodulator | Steroidal Drug

Description:

Deflazacort (Cas No.: 14484-47-0) is derivative of prednisolone and a glucocorticoid-class corticosteroid which is mainly used to treat inflammation and autoimmune conditions. Deflazacort I widely used to prevent diseases such as rheumatoid arthritis , asthma, Duchenne muscular dystrophy (DMD) , inflammatory bowel diseases, and carious allergic disorders.

Deflazacort shows potent anti-inflammatory and immunosuppressive effects with reduce tendency to cause weight gain and bone demineralization as compared to other corticosteroids. Deflazacort act by suppressing the release of inflammatory mediators and modulating immune system responses due to which it is highly effective in both acute and chronic conditions.

Chemox Pharma is leading manufacturer of Deflazacort [CAS No: 14484-47-0] and ensures high-purity products with highest level of compliance. Chemox Pharma offers global regulatory supports and reliable supply chain solutions – establishing us as a trusted partner by pharmaceutical companies over 90 countries, reflecting global footprints and reputation.

 

Applications

Sr. No. Description Application
1 Corticosteroid anti-inflammatory API Inflammatory disorder treatment
2 Immunosuppressive pharmaceutical ingredient Autoimmune disease therapy
3 Glucocorticoid drug substance Muscular dystrophy management
4 Anti-allergic corticosteroid API Allergic condition treatment
5 Steroidal therapeutic API Rheumatic and inflammatory diseases

Deflazacort is widely used by pharmaceutical manufacturers in formulations for inflammatory, autoimmune, and corticosteroid therapeutic applications.

Product Specifications

Deflazacort API should be handled according to standard pharmaceutical material safety and industrial hygiene procedures. Appropriate protective measures must be followed during handling and processing of the corticosteroid active pharmaceutical ingredient in GMP manufacturing environments.

  • Use appropriate personal protective equipment (PPE)

  • Avoid inhalation of powder and contact with skin or eyes

  • Handle in controlled pharmaceutical manufacturing areas

  • Follow GMP material handling procedures

  • Refer to Safety Data Sheet (SDS) for detailed safety guidance

This API is intended exclusively for pharmaceutical manufacturing and formulation use.

Mechanism of Actions

Deflazacort is a synthetic glucocorticoid corticosteroid that exerts anti-inflammatory and immunosuppressive effects by binding to intracellular glucocorticoid receptors. This interaction modulates gene transcription, reducing production of pro-inflammatory mediators and suppressing immune responses. Its mechanism supports therapeutic use in inflammatory disorders, autoimmune diseases, and muscular dystrophy management.

Safety Precautions

  • Handle in approved pharmaceutical manufacturing facilities

  • Avoid exposure without protective equipment

  • Prevent dust generation and inhalation

  • Follow GMP containment procedures

  • Dispose according to regulatory guidelines

Storage

  • Store in tightly closed containers

  • Protect from moisture and light

  • Maintain controlled room temperature

  • Keep in designated API storage areas

  • Follow GMP warehouse practices

FAQs

What is Deflazacort API used for?

Deflazacort API is used in pharmaceutical formulations as a corticosteroid for treating inflammatory disorders, autoimmune diseases, and muscular dystrophy.

Is Chemox Pharma a Deflazacort API manufacturer in India?

Yes, Chemox Pharma is a WHO-GMP certified Deflazacort API manufacturer and supplier in India serving global pharmaceutical companies.

What is the CAS number of Deflazacort?

The CAS number of Deflazacort API is 14484-47-0.

What is the therapeutic class of Deflazacort API?

Deflazacort belongs to the corticosteroid (glucocorticoid) class of anti-inflammatory and immunosuppressive therapeutic agents.

How should Deflazacort API be stored?

It should be stored in tightly closed containers at controlled room temperature, protected from moisture and light, following pharmaceutical storage guidelines.

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