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CITICOLINE SODIUM

CPPL / Product / CITICOLINE SODIUM

CITICOLINE SODIUM

CITICOLINE SODIUM API
Chemical name: Acticolin. Cytidine-5′-diphosphocholine Sodium, sodium salt / 5′-O-[({[2-(Triméthylammonio) éthoxy]phosphinato}oxy) phosphinato] cytidine de sodium or Citidine 5′-Diphosphocholine Sodium
Cas number: 33818-15-4
Molecular formula: C14H25N4NaO11P2
Molecular weight: 510.31
Therapeutic uses: Nootropic, Psychostimulants
Specifications: IH/IP/USP
Appearance: White to off-white powder
Storage: Room temperature <25°C, tightly sealed dry area.
Therapeutic Class: Nootropic Agent | Neuroprotective Compound | CNS Stimulant (non-habit forming) | Phosphatidylcholine Precursor

Description:

Citicoline Sodium [Cas No: 33818-15-4], is also known as CDP- Choline Sodium Salt, which is a main intermediate in the synthesis of phosphatidylcholine. Citicoline Sodium also plays a key role in maintaining brain cell membrane integrity and supports neurotransmitter synthesis. The use of Citicoline Sodium is mainly in improving memory, mental clarity, focus, and supports recovery from stroke or brain injuries.

Research has shown that Citicoline Sodium increases dopamine receptor densities which results in enhanced dopaminergic activity that is vital pathway for motivation, memory and mood regulation. Additionally, Citicoline Sodium stimulates the secretion of Adrenocorticotropic Hormone [ACTH], as well as increases other HPA axis hormones such as LH, FSH, GH and TSH.

Chemox Pharma is a leading manufacturer of Citicoline Sodium and follows all worldwide regulatory standards such as WHO-GMP, FDA, DCGI. We also house a well-equipped R&D Centre, focused on process development, quality improvement, and cost optimization—empowering us to meet the evolving needs of the global pharmaceutical industry.

Applications

Sr. No. Description Application
1 Neuroprotective API Stroke recovery formulations
2 Nootropic drug substance Cognitive impairment therapy
3 CDP-choline pharmaceutical ingredient Neurodegenerative disorder treatment
4 Neurological therapeutic API Brain injury recovery drugs
5 Cognitive enhancer API Memory and cognition support formulations

Citicoline Sodium is widely used by pharmaceutical manufacturers in neurology and cognitive health formulations.

Product Specifications

Citicoline Sodium API should be handled according to standard pharmaceutical material safety and industrial hygiene procedures. Appropriate protective measures must be followed during handling and processing of the neurological active pharmaceutical ingredient in GMP manufacturing environments.

  • Use appropriate personal protective equipment (PPE)

  • Avoid inhalation of powder and contact with skin or eyes

  • Handle in controlled pharmaceutical manufacturing areas

  • Follow GMP material handling procedures

  • Refer to Safety Data Sheet (SDS) for detailed safety guidance

This API is intended exclusively for pharmaceutical manufacturing and formulation use.

Mechanism of Actions

Citicoline Sodium (CDP-choline) is a precursor in phosphatidylcholine biosynthesis, essential for neuronal cell membrane repair and integrity. It enhances acetylcholine synthesis, supports phospholipid metabolism, and reduces neuronal damage by stabilizing cell membranes and reducing free radical formation. These actions contribute to neuroprotection and cognitive function improvement in neurological disorders.

Safety Precautions

  • Handle in approved pharmaceutical manufacturing facilities

  • Avoid exposure without protective equipment

  • Prevent dust generation and inhalation

  • Follow GMP containment procedures

  • Dispose according to regulatory guidelines

Storage

  • Store in tightly closed containers

  • Protect from moisture and light

  • Maintain controlled room temperature

  • Keep in designated API storage areas

  • Follow GMP warehouse practices

FAQs

What is Citicoline Sodium API used for?

Citicoline Sodium API is used in pharmaceutical formulations for neurological conditions such as stroke recovery, cognitive impairment, and neurodegenerative disorders.

Is Chemox Pharma a Citicoline Sodium API manufacturer in India?

Yes, Chemox Pharma is a WHO-GMP certified Citicoline Sodium API manufacturer and supplier in India serving global pharmaceutical companies.

What is the CAS number of Citicoline Sodium?

The CAS number of Citicoline Sodium API is 33818-15-4.

What is the therapeutic class of Citicoline Sodium API?

Citicoline Sodium belongs to the neuroprotective and nootropic class of neurological therapeutic agents used in cognitive and brain disorder management.

How should Citicoline Sodium API be stored?

It should be stored in tightly closed containers at controlled room temperature, protected from moisture and light, following pharmaceutical storage guidelines.

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