8-Bromo-7-but-2-ynyl-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]purine-2,6-dione (CAS 853029-57-9)

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8-Bromo-7-but-2-ynyl-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]purine-2,6-dione (CAS 853029-57-9)

Linagliptin Intermediate

API Name / End Use: Linagliptin (Intermediate – BBQ)

CAS Number: 853029-57-9

Molecular Formula: C20H17BrN6O2

Molecular Weight: 453.29 g/mol

Appearance: White to off-white crystalline powder

Storage: Store in a cool, dry place at room temperature (<25°C), protected from light and moisture

Description:

Chemox Pharma is a leading supplier and manufacturer of 8-Bromo-7-but-2-ynyl-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]purine-2,6-dione (CAS No.: 853029-57-9), commonly referred to as Linagliptin Intermediate – BBQ. This key intermediate is used in the synthesis of Linagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor widely prescribed for the treatment of type 2 diabetes mellitus.

As an ISO 9001:2015 certified company, Chemox Pharma ensures the supply of high-quality intermediates manufactured under strict global regulatory guidelines (DCGI, WHO-GMP, FDA). Each batch is produced with high purity, consistency, and complete documentation support to meet the requirements of international pharmaceutical companies.

With a strong focus on quality assurance, transparency, and compliance, Chemox Pharma is a trusted partner for global pharma industries. Our advanced R&D Centre enables process development, optimization, and cost-effective solutions, ensuring reliable supply and regulatory excellence.

Contact us today for sourcing Linagliptin Intermediate – BBQ (CAS No.: 853029-57-9) with competitive pricing, assured quality, and timely delivery.

Applications

Sr. No. Description Application
1 Purine-based heterocyclic intermediate API synthesis
2 Quinazoline-linked building block Medicinal chemistry research
3 Advanced pharmaceutical intermediate Drug discovery synthesis
4 Functional purine derivative Specialty chemical manufacturing
5 Complex heterocyclic compound Pharmaceutical R&D

This compound is widely used in pharmaceutical research and development as a purine-quinazoline heterocyclic intermediate.

Product Specifications

8-Bromo-7-but-2-ynyl-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]purine-2,6-dione should be handled according to standard pharmaceutical intermediate and laboratory chemical safety procedures. Proper industrial hygiene practices and protective measures must be followed during handling, processing, and synthesis operations.

  • Use appropriate personal protective equipment (PPE)

  • Avoid inhalation of dust and contact with skin or eyes

  • Handle in controlled, well-ventilated environments

  • Follow chemical safety handling protocols

  • Refer to Safety Data Sheet (SDS) for detailed safety information

This compound is intended strictly for pharmaceutical intermediate and research use.

Mechanism of Actions

As a complex heterocyclic pharmaceutical intermediate, 8-Bromo-7-but-2-ynyl-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]purine-2,6-dione does not exhibit direct pharmacological activity. It functions as a structurally specialized purine-quinazoline building block in multi-step organic synthesis pathways for advanced active pharmaceutical ingredients. Its brominated purine core and quinazoline moiety enable selective substitution and coupling reactions essential in medicinal chemistry and drug development.

Safety Precautions

  • Handle in approved chemical or pharmaceutical facilities

  • Avoid exposure without protective equipment

  • Prevent dust generation and inhalation

  • Follow laboratory and industrial chemical safety procedures

  • Dispose according to regulatory guidelines

Storage

  • Store in tightly closed containers

  • Protect from moisture and light

  • Maintain cool, dry storage conditions

  • Keep in designated chemical storage areas

  • Follow standard warehouse practices

FAQs

What is 8-Bromo-7-but-2-ynyl-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]purine-2,6-dione used for?

It is a complex heterocyclic pharmaceutical intermediate used in advanced API synthesis, medicinal chemistry research, and drug discovery development.

Is Chemox Pharma a manufacturer of CAS 853029-57-9?

Yes, Chemox Pharma manufactures and supplies 8-Bromo-7-but-2-ynyl-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]purine-2,6-dione (CAS 853029-57-9) with high purity for pharmaceutical research and synthesis applications.

What type of compound is this molecule?

It is a brominated purine-quinazoline heterocyclic intermediate used as a specialized building block in pharmaceutical and medicinal chemistry synthesis.

What is the CAS number of this pharmaceutical intermediate?

The CAS number is 853029-57-9.

How should this heterocyclic intermediate be stored?

It should be stored in tightly sealed containers in a cool, dry place protected from moisture and light, following standard chemical storage practices.

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