4-(Chloromethyl)-5-methyl-1,3-dioxol-2-one (CAS 80841-78-7)

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4-(Chloromethyl)-5-methyl-1,3-dioxol-2-one (CAS 80841-78-7)

intermediate

API Name / End Use: Olmesartan (Intermediate – DMDO-CL)

CAS Number: 80841-78-7

Molecular Formula: C5H7ClO3

Molecular Weight: 150.56 g/mol

Appearance: Clear to pale yellow liquid / low-melting crystalline solid

Storage: Store in a cool, dry, and well-ventilated area at room temperature (<25°C), away from direct light and moisture

Description:

Chemox Pharma is a reliable manufacturer and supplier of 4-(Chloromethyl)-5-methyl-1,3-dioxol-2-one (CAS No.: 80841-78-7), widely known as Olmesartan Intermediate – DMDO-CL. This compound plays a crucial role in the synthesis of Olmesartan Medoxomil, an angiotensin II receptor blocker (ARB) used in the treatment of hypertension.

As an ISO 9001:2015 certified Indian company, Chemox Pharma specializes in the production and supply of high-quality pharmaceutical intermediates. Our manufacturing facilities operate under strict global regulatory standards (DCGI, WHO-GMP, FDA), ensuring consistency, purity, and compliance for both R&D and commercial-scale requirements.

With a strong commitment to quality assurance, transparency, and regulatory compliance, Chemox Pharma has become a trusted partner for global pharmaceutical industries. Our dedicated R&D centre focuses on process innovation, quality enhancement, and cost optimization to meet the growing demands of international markets.

Applications

Sr. No. Description Application
1 Dioxolone chemical intermediate API synthesis
2 Reactive chloromethyl compound Pharmaceutical intermediate production
3 Heterocyclic carbonate intermediate Fine chemical synthesis
4 Functionalized organic building block Medicinal chemistry manufacturing
5 Specialty chemical intermediate Agrochemical and pharmaceutical synthesis

4-(Chloromethyl)-5-methyl-1,3-dioxol-2-one is widely used in pharmaceutical and fine chemical manufacturing as a reactive carbonate intermediate.

Product Specifications

4-(Chloromethyl)-5-methyl-1,3-dioxol-2-one should be handled in accordance with standard chemical and pharmaceutical intermediate safety procedures. Appropriate industrial hygiene practices and protective measures must be followed during handling, processing, and manufacturing operations.

  • Use suitable personal protective equipment (PPE) during handling

  • Avoid inhalation of vapors or dust and contact with skin or eyes

  • Handle in well-ventilated controlled environments

  • Follow chemical material handling protocols

  • Refer to Safety Data Sheet (SDS) for detailed safety guidance

This material is intended strictly for industrial and pharmaceutical intermediate use.

Mechanism of Actions

As a pharmaceutical intermediate, 4-(Chloromethyl)-5-methyl-1,3-dioxol-2-one does not possess therapeutic pharmacological activity. It functions as a reactive chloromethyl-substituted dioxolone building block in multi-step organic synthesis pathways for active pharmaceutical ingredients and specialty chemicals. Its functional groups enable controlled substitution and derivatization reactions essential in medicinal chemistry and drug intermediate manufacturing.

Safety Precautions

  • Handle in approved chemical manufacturing facilities

  • Avoid exposure without protective equipment

  • Prevent inhalation and skin contact

  • Follow industrial chemical safety procedures

  • Dispose according to regulatory guidelines

Storage

  • Store in tightly closed containers

  • Protect from moisture and heat

  • Maintain cool, dry storage conditions

  • Keep in designated chemical storage areas

  • Follow standard warehouse practices

FAQs

What is 4-(Chloromethyl)-5-methyl-1,3-dioxol-2-one used for?

4-(Chloromethyl)-5-methyl-1,3-dioxol-2-one is a pharmaceutical and fine chemical intermediate used in the synthesis of active pharmaceutical ingredients and specialty chemical compounds.

Is Chemox Pharma a manufacturer of CAS 80841-78-7?

Yes, Chemox Pharma manufactures and supplies 4-(Chloromethyl)-5-methyl-1,3-dioxol-2-one (CAS 80841-78-7) with high purity for pharmaceutical and chemical manufacturing applications.

What is the CAS number of this dioxolone intermediate?

The CAS number of 4-(Chloromethyl)-5-methyl-1,3-dioxol-2-one is 80841-78-7.

What type of compound is this chemical?

It is a chloromethyl-substituted dioxolone heterocyclic intermediate used as a reactive building block in pharmaceutical and fine chemical synthesis.

How should this pharmaceutical intermediate be stored?

It should be stored in tightly sealed containers in a cool, dry place protected from moisture and heat, following standard chemical storage practices.

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