API Name / End Use: Dapagliflozin (Intermediate)
CAS Number: 461432-25-2-7
Molecular Formula: C28H31ClO10
Molecular Weight: 563.99 g/mol
Appearance: White to off-white crystalline solid
Storage: Store in a cool, dry place at room temperature (<25°C), protected from light and moisture
Chemox Pharma is a trusted global supplier and manufacturer of (2R,3R,4R,5S,6S)-2-(Acetoxymethyl)-6-[4-chloro-3-(4-ethoxybenzyl)phenyl]tetrahydro-2H-pyran-3,4,5-triyl triacetate (CAS No.: 461432-25-2-7), a critical intermediate in the synthesis of Dapagliflozin, an SGLT2 inhibitor widely used in the treatment of type 2 diabetes mellitus.
As an ISO 9001:2015 certified company, Chemox Pharma specializes in providing high-quality APIs and intermediates for both research purposes and large-scale commercial production. Every batch is manufactured with strict adherence to global regulatory requirements (DCGI, WHO-GMP, FDA), ensuring consistency, purity, and compliance.
Chemox Pharma is committed to quality assurance, transparency, and regulatory excellence, making us a trusted partner for global pharmaceutical industries. With a well-equipped R&D centre, we continuously focus on process optimization, cost efficiency, and quality improvements.
| Sr. No. | Description | Application |
|---|---|---|
| 1 | Chiral pyran intermediate | API synthesis |
| 2 | Protected carbohydrate-like building block | Medicinal chemistry |
| 3 | Acetylated heterocyclic intermediate | Pharmaceutical R&D |
| 4 | Stereochemically defined organic intermediate | Drug development |
| 5 | Advanced pharmaceutical intermediate | Specialty chemical synthesis |
This compound is widely used in pharmaceutical research and development as a chiral tetrahydropyran-based intermediate for complex API synthesis.
(2R,3R,4R,5S,6S)-2-(Acetoxymethyl)-6-[4-chloro-3-(4-ethoxybenzyl)phenyl]tetrahydro-2H-pyran-3,4,5-triyl triacetate should be handled in accordance with standard pharmaceutical intermediate and laboratory chemical safety procedures. Appropriate industrial hygiene and protective measures must be followed during handling and synthesis operations.
Use appropriate personal protective equipment (PPE)
Avoid inhalation of dust and contact with skin or eyes
Handle in controlled, well-ventilated environments
Follow chemical handling and containment protocols
Refer to Safety Data Sheet (SDS) for detailed safety information
This compound is intended strictly for pharmaceutical intermediate and research use.
As a chiral pharmaceutical intermediate, (2R,3R,4R,5S,6S)-2-(Acetoxymethyl)-6-[4-chloro-3-(4-ethoxybenzyl)phenyl]tetrahydro-2H-pyran-3,4,5-triyl triacetate does not exhibit direct pharmacological activity. It functions as a stereochemically defined tetrahydropyran building block in multi-step organic synthesis pathways for active pharmaceutical ingredients. Its protected hydroxyl groups and aromatic substituents enable selective deprotection, substitution, and coupling reactions essential in medicinal chemistry and drug development.
Handle in approved chemical or pharmaceutical facilities
Avoid exposure without protective equipment
Prevent dust formation and inhalation
Follow laboratory and industrial safety procedures
Dispose according to regulatory guidelines
Store in tightly closed containers
Protect from moisture and light
Maintain cool, dry storage conditions
Keep in designated chemical storage areas
Follow standard warehouse practices
It is a chiral pharmaceutical intermediate used in advanced API synthesis, medicinal chemistry research, and stereochemically controlled drug development.
Yes, Chemox Pharma manufactures and supplies (2R,3R,4R,5S,6S)-2-(Acetoxymethyl)-6-[4-chloro-3-(4-ethoxybenzyl)phenyl]tetrahydro-2H-pyran-3,4,5-triyl triacetate (CAS 461432-25-2) with high purity for pharmaceutical synthesis applications.
It is a stereochemically defined tetrahydropyran-based chiral pharmaceutical intermediate used as a building block in complex API synthesis.
The CAS number is 461432-25-2.
It should be stored in tightly sealed containers in a cool, dry place protected from moisture and light, following standard chemical storage practices.
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