Cholesterol is known as the ‘silent killer’ because it has no apparent symptoms in the early stages. It often results in heart attacks and strokes. However, with regular medicine, one can reduce cholesterol and avoid other heart conditions. Fenofibrate API creates cholesterol medicines like Antara, Lipofen, and more. In this blog, we will discuss how it works and its uses!
What is Fenofibrate API?
Fenofibrate API is an FDA-approved ingredient used to create cholesterol medicine and triglyceride treatment. It is part of the lipid-modifying drug class: Fibrates. They are known to reduce cholesterol and triglycerides in the body. Therefore, it is often used by patients who suffer from high blood pressure and heart conditions due to cholesterol and blood circulation problems.
The chemical structure of Fenofibrate is C20H21ClO4. It is available under the brand names Antara, Cholib, Fenoglide, Lipidil Supra, Lipofen, Pravafenix, Tricor, and Triglide. If you want to create any of these medicines, you need high-quality Fenofibrate APIs, available at Chemox Pharma.
The growing stressful work environment and unhealthy eating habits increase the risk of cardiovascular problems like high cholesterol. Therefore, cholesterol medicines like Fenofibrate are essentials for managing these risks. As per reports, in 2024, the global fenofibrate drug market was valued at USD 3.42 billion. This figure is expected to reach USD 5.67 billion by 2034.
It is one of the most effective medicines for controlling the body’s lipid profile. Furthermore, its long half-life, efficacy, and affordable pricing have made it a popular medicine for cholesterol control.
What are the uses of Fenofibrate?
The following are three conditions where Fenofibrate is found to be most effective.
Hypertriglyceridemia
Hypertriglyceridemia occurs when a patient has significantly higher triglyceride levels in the blood. It leads to diverse health risks such as cardiovascular and pancreatic problems. It affects our bodily functions and daily activities.
Fenofibrate is known for reducing the amount of triglycerides and boosting good cholesterol. It helps the patient control their condition and avoid worsening it. Triglyceride treatment, along with lifestyle changes, can help heart patients live a healthier life.
Hypercholesterolemia
Hypercholesterolemia occurs when the patient has excessive cholesterol in the blood. It leads to plaque formation that might cause your arteries to rupture or narrow down. It affects your blood flow and often causes heart attacks and strokes. Hypercholesterolemia occurs when the low-density lipoprotein (LDL), also known as bad cholesterol, is in excess as compared to the high-density lipoprotein (HDL), which is good cholesterol.
Fibrates are known for breaking down the LDLs to reduce bad cholesterol and increase good cholesterol in the blood. Therefore, it is used for heart patients with high cholesterol.
Mixed Dyslipidemia
Mixed Dyslipidemia occurs when the patient has abnormal lipid levels in their blood. The patients have higher triglyceride and LDL (bad cholesterol) and lower levels of good cholesterol (HDL). It leads to cardiovascular risks like plaque formation, heart attack, and strokes. Apart from heart patients, Dyslipidemia is often seen in patients with type 2 diabetes and weak metabolism.
Fenofibrate breaks down the triglyceride and bad cholesterol, leading to more good cholesterol in the bloodstream.
How does Fenofibrate help reduce cholesterol?
Fenofibrate reduces triglycerides and bad cholesterol by activating the peroxisome proliferator-activated receptor alpha (PPARα). These receptors hydrolyze the lipids and reduce the apoprotein C-III, which is responsible for preventing lipid breakdown.
It has a half-life of 19-27 hours. Therefore, it is one of the best cholesterol medicines. Its long-term effect helps manage the lipid profile.
Buy Fenofibrate API with a custom pharmacopoeia from Chemox Pharma!
Different countries might have unique pharmacopoeia needs. Therefore, Chemox Pharma is here to help you create Fenofibrate API in custom pharmacopoeia standards such as IP, BP, and USP. We are a WHO-GMP-certified API manufacturing company in India.
Our team of skilled scientists creates high-quality APIs and Intermediates based on your unique requirements. This enables you to create your medicines and expand your target markets. We have customers in 20+ countries with our 19 APIs available in the market. We can also create custom packaging to ensure your pharma products reach you safely.
Conclusion
Fenofibrate API is used to create triglyceride treatments and cholesterol medicines. It works by activating the peroxisome proliferator-activated receptor alpha (PPARα), which breaks down the triglyceride and LDL, while increasing good cholesterol. Therefore, it is used to treat cardiovascular problems like Hypertriglyceridemia, Hypercholesterolemia, and Mixed Dyslipidemia. All these problems often lead to heart attack and stroke. Chemox Pharma is a WHO-GMP-approved API manufacturing company in India that can help you create Fenofibrate API with a customizable pharmacopoeia. Contact us now to know more!
FAQ
What are the benefits of Fenofibrate API?
The following are a few benefits of using Fenofibrate APIs:
- Reduces triglycerides
- Reduces Low-Density Lipids (LDL), aka bad cholesterol
- Increases High-Density Lipids (HDL), aka good cholesterol
They have good tolerability and half-life. Therefore, they are often used in combination therapy for heart patients.
Is Fenofibrate effective for cholesterol medicine?
Yes! Fenofibrate is used to control cholesterol in the bloodstream. It hydrolyzes the lipids to reduce the Low-Density Lipids (bad cholesterol). Thus, the body benefits from an increase in good cholesterol to support healthy cardiovascular activities. Chemox Pharma offers the best APIs to create cholesterol medicines.
Where to find high-quality Fenofibrate in India?
The efficacy of any medicine depends on the quality of the APIs. Chemox Pharma is one of the most trusted, WHO-GMP-approved API manufacturers in India, and it has 19 APIs, including the Fenofibrate API. We can help you create a custom API based on IP/BP/USP pharmacopoeia standards at affordable prices. We can also create custom packaging based on your needs. Contact us now with your queries!
Why should pharma companies focus on Fenofibrate API?
The stressful lifestyle and unhealthy eating habits are resulting in more heart failures and cardiovascular problems. The younger generation is also found to be suffering from heart problems, such as higher cholesterol and triglycerides. Therefore, there has been a surge in demand for cholesterol medicine like Fenofibrate. High-quality Fenofibrate API helps you create medicines with better efficacy and half-life. Chemox Pharma is here to create APIs with custom pharmacopoeia standards. Contact us to know more.
